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NHLH1 Antibody

Product Specifications

Background

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCLThe helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040) .

NCBI Gene ID

4807

Swiss Prot

Q02575

Accession Number

NP_005589

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NHLH1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer, Neuroscience

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10407 - Fetal Heart Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NHLH1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

14 kDa

Applications Notes

NHLH1 antibody can be used for detection of NHLH1 by ELISA at 1:1562500. NHLH1 antibody can be used for detection of NHLH1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

NHLH1

NCBI Official Name

Nescient helix loop helix 1

NCBI Organism

Homo sapiens

Background Reference 01

Manetopoulos, C., (2003) Biochem. Biophys. Res. Commun. 307 (4), 891-899.

Other Product Names

NHLH1, HEN1, NSCL, NSCL1, bHLHa35

Tested Applications

ELISA, WB

Protein ID

5031943

Physical Properties

Liquid

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