GTF2E1 Antibody
Product Specifications
Background
GTF2E1 belongs to the TFIIE alpha subunit family. It recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
NCBI Gene ID
2960
Swiss Prot
P29083
Accession Number
NP_005504
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTF2E1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GTF2E1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=27-249
Calculated Molecular Weight
49 kDa
Applications Notes
GTF2E1 antibody can be used for detection of GTF2E1 by ELISA at 1:312500. GTF2E1 antibody can be used for detection of GTF2E1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GTF2E1
NCBI Official Name
General transcription factor IIE, polypeptide 1, alpha 56kDa
NCBI Organism
Homo sapiens
Background Reference 01
Okuda, M., (2008) EMBO J. 27 (7), 1161-1171.
Other Product Names
GTF2E1, FE, TF2E1, TFIIE-A
Tested Applications
ELISA, WB
Protein ID
144922725
Physical Properties
Liquid
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