STXBP1 Antibody
Product Specifications
Background
STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4.
NCBI Gene ID
6812
Swiss Prot
P61764
Accession Number
NP_001027392
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STXBP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store STXBP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
67 kDa
Applications Notes
STXBP1 antibody can be used for detection of STXBP1 by ELISA at 1:12500. STXBP1 antibody can be used for detection of STXBP1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
STXBP1
NCBI Official Name
Syntaxin binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Saitsu, H., (2008) Nat. Genet. 40 (6), 782-788.
Other Product Names
STXBP1, MUNC18-1, UNC18, hUNC18, rbSec1, P67, NSEC1, RBSEC1
Tested Applications
ELISA, WB
Protein ID
73760415
Physical Properties
Liquid
Curated Selection
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