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OPRK1 Antibody

Product Specifications

Background

OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions.

NCBI Gene ID

4986

Swiss Prot

P41145

Accession Number

NP_000903

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OPRK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction, Immunology

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store OPRK1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

43 kDa

Applications Notes

OPRK1 antibody can be used for detection of OPRK1 by ELISA at 1:62500. OPRK1 antibody can be used for detection of OPRK1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

OPRK1

NCBI Official Name

Opioid receptor, kappa 1

NCBI Organism

Homo sapiens

Background Reference 01

Edenberg, H.J., (2008) Hum. Mol. Genet. 17 (12), 1783-1789.

Other Product Names

OPRK1, KOR, OPRK, KOR-1, K-OR-1

Tested Applications

ELISA, WB

Protein ID

39725940

Physical Properties

Liquid

Curated Selection

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