OPRK1 Antibody
Product Specifications
Background
OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions.
NCBI Gene ID
4986
Swiss Prot
P41145
Accession Number
NP_000903
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OPRK1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store OPRK1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
43 kDa
Applications Notes
OPRK1 antibody can be used for detection of OPRK1 by ELISA at 1:62500. OPRK1 antibody can be used for detection of OPRK1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
OPRK1
NCBI Official Name
Opioid receptor, kappa 1
NCBI Organism
Homo sapiens
Background Reference 01
Edenberg, H.J., (2008) Hum. Mol. Genet. 17 (12), 1783-1789.
Other Product Names
OPRK1, KOR, OPRK, KOR-1, K-OR-1
Tested Applications
ELISA, WB
Protein ID
39725940
Physical Properties
Liquid
Curated Selection
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