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HTR5A Antibody

Product Specifications

Background

The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. HTR5A is a member of 5-hydroxytryptamine (serotonin) receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1213 BC112021.1 1-1213 1214-1342 AC093726.3 158913-159041 1343-1935 AC092628.3 1996-2588 1936-2400 AK094255.1 2447-2911

NCBI Gene ID

3361

Swiss Prot

P47898

Accession Number

NP_076917

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR5A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HTR5A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

40 kDa

Applications Notes

HTR5A antibody can be used for detection of HTR5A by ELISA at 1:312500. HTR5A antibody can be used for detection of HTR5A by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

HTR5A

NCBI Official Name

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

NCBI Organism

Homo sapiens

Background Reference 01

Wilkie, M.J., (er) Pharmacogenomics J. (2008) In press.

Other Product Names

HTR5A, 5-HT5A, MGC138226

Tested Applications

ELISA, WB

Protein ID

13236497

Physical Properties

Liquid

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