FN3KRP Antibody
Product Specifications
Background
FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]) .
NCBI Gene ID
79672
Swiss Prot
Q9HA64
Accession Number
NP_078895
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FN3KRP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FN3KRP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=27-199
Calculated Molecular Weight
34 kDa
Applications Notes
FN3KRP antibody can be used for detection of FN3KRP by ELISA at 1:1562500. FN3KRP antibody can be used for detection of FN3KRP by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
FN3KRP
NCBI Official Name
Fructosamine 3 kinase related protein
NCBI Organism
Homo sapiens
Background Reference 01
Szwergold, B., (2007) Biochem. Biophys. Res. Commun. 361 (4), 870-875.
Other Product Names
FN3KRP, FLJ12171, FN3KL
Tested Applications
ELISA, WB
Protein ID
20149680
Physical Properties
Liquid
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