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DDAH2 Antibody

Product Specifications

Background

DDAH2 hydrolyzes N (G), N (G) -dimethyl-L-arginine (ADMA) and N (G) -monomethyl-L-arginine (MMA) which act as inhibitors of NOS. DDAH2 has therefore a role in nitric oxide generation.This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NCBI Gene ID

23564

Swiss Prot

O95865

Accession Number

NP_039268

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDAH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Immunology

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DDAH2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

31 kDa

Applications Notes

DDAH2 antibody can be used for detection of DDAH2 by ELISA at 1:1562500. DDAH2 antibody can be used for detection of DDAH2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

DDAH2

NCBI Official Name

Dimethylarginine dimethylaminohydrolase 2

NCBI Organism

Homo sapiens

Background Reference 01

Kim, Y.J., (2008) Twin Res Hum Genet 11 (1), 77-83.

Other Product Names

DDAH2, DDAH, DDAHII, G6a, NG30, HEL-S-277

Tested Applications

ELISA, WB

Protein ID

7524354

Physical Properties

Liquid

Frequently Asked Questions

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