TINF2 Antibody
Product Specifications
Background
TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
NCBI Gene ID
26277
Swiss Prot
Q9BSI4
Accession Number
NP_001092744
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TINF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TINF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
50 kDa
Applications Notes
TINF2 antibody can be used for detection of TINF2 by ELISA at 1:1562500. TINF2 antibody can be used for detection of TINF2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TINF2
NCBI Official Name
TERF1 (TRF1) -interacting nuclear factor 2
NCBI Organism
Homo sapiens
Background Reference 01
Kim, S.H., (2008) J. Cell Biol. 181 (3), 447-460.
Other Product Names
TINF2, TIN2, DKCA3
Tested Applications
ELISA, WB
Protein ID
151101266
Physical Properties
Liquid
Frequently Asked Questions
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