C2orf3 Antibody

The first mRNA transcript isolated for C2orf3 gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204) . C2orf3 belongs to the GCF family. It is a factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204) . A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store C2orf3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

C2orf3 antibody can be used for detection of C2orf3 by ELISA at 1:12500. C2orf3 antibody can be used for detection of C2orf3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.