HTRA4 Antibody
Product Specifications
Background
HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
NCBI Gene ID
203100
Swiss Prot
P83105
Accession Number
NP_710159
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTRA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HTRA4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
51 kDa
Applications Notes
HTRA4 antibody can be used for detection of HTRA4 by ELISA at 1:312500. HTRA4 antibody can be used for detection of HTRA4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HTRA4
NCBI Official Name
HtrA serine peptidase 4
NCBI Organism
Homo sapiens
Background Reference 01
Clausen, T., (2002) Mol. Cell 10 (3), 443-455.
Other Product Names
HTRA4, FLJ90724
Tested Applications
ELISA, WB
Protein ID
24308541
Physical Properties
Liquid
Frequently Asked Questions
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