GSPT2 Antibody
Product Specifications
Background
GSPT2 is closely related to GSPT1, a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1, functions as a polypeptide chain release factor.GSPT2 is closely related to GSPT1 (MIM 139259), a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1 (MIM 600285), functions as a polypeptide chain release factor.
NCBI Gene ID
23708
Swiss Prot
Q8IYD1
Accession Number
NP_060564
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSPT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GSPT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
69 kDa
Applications Notes
GSPT2 antibody can be used for detection of GSPT2 by ELISA at 1:62500. GSPT2 antibody can be used for detection of GSPT2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GSPT2
NCBI Official Name
G1 to S phase transition 2
NCBI Organism
Homo sapiens
Background Reference 01
Chauvin, C., (2005) Mol. Cell. Biol. 25 (14), 5801-5811.
Other Product Names
GSPT2, FLJ10441, GST2, eRF3b, ERF3B
Tested Applications
ELISA, WB
Protein ID
46094014
Physical Properties
Liquid
Curated Selection
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