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GSPT2 Antibody

Product Specifications

Background

GSPT2 is closely related to GSPT1, a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1, functions as a polypeptide chain release factor.GSPT2 is closely related to GSPT1 (MIM 139259), a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1 (MIM 600285), functions as a polypeptide chain release factor.

NCBI Gene ID

23708

Swiss Prot

Q8IYD1

Accession Number

NP_060564

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSPT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1219 - MCF7 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GSPT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

69 kDa

Applications Notes

GSPT2 antibody can be used for detection of GSPT2 by ELISA at 1:62500. GSPT2 antibody can be used for detection of GSPT2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

GSPT2

NCBI Official Name

G1 to S phase transition 2

NCBI Organism

Homo sapiens

Background Reference 01

Chauvin, C., (2005) Mol. Cell. Biol. 25 (14), 5801-5811.

Other Product Names

GSPT2, FLJ10441, GST2, eRF3b, ERF3B

Tested Applications

ELISA, WB

Protein ID

46094014

Physical Properties

Liquid

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