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C2orf25 Antibody

Product Specifications

Background

The function of C2orf25 remains unknown.Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to adenosylcobalamin in mitochondria and to methylcobalamin in cytoplasm is necessary for homeostasis of methylmalonic acid and homocysteine. C2ORF25 encodes a protein involved in an early step of cobalamin metabolism (Coelho et al., 2008 [PubMed 18385497]) .

NCBI Gene ID

27249

Swiss Prot

Q9H3L0

Accession Number

NP_056517

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C2orf25.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store C2orf25 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

33 kDa

Applications Notes

C2orf25 antibody can be used for detection of C2orf25 by ELISA at 1:62500. C2orf25 antibody can be used for detection of C2orf25 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

MMADHC

NCBI Official Name

Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria

NCBI Organism

Homo sapiens

Background Reference 01

Coelho, D., (2008) N. Engl. J. Med. 358 (14), 1454-1464.

Other Product Names

C2orf25, CL25022, cblD, C2orf25

Tested Applications

ELISA, WB

Protein ID

7661548

Physical Properties

Liquid

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