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HISPPD1 Antibody

Product Specifications

Background

Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively.Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]) .

NCBI Gene ID

23262

Swiss Prot

O43314

Accession Number

NP_056031

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HISPPD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HISPPD1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=26-980

Calculated Molecular Weight

138 kDa

Applications Notes

HISPPD1 antibody can be used for detection of HISPPD1 by ELISA at 1:1562500. HISPPD1 antibody can be used for detection of HISPPD1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PPIP5K2

NCBI Official Name

Diphosphoinositol pentakisphosphate kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Choi, J.H., (2007) J. Biol. Chem. 282 (42), 30763-30775.

Other Product Names

HISPPD1, FLJ21506, KIAA0433, PPIP5K2, VIP2, IP7K2, HISPPD1

Tested Applications

ELISA, WB

Protein ID

41281583

Physical Properties

Liquid

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