CDC42EP4 Antibody
Product Specifications
Background
CDC42EP4 is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. The protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, the protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
NCBI Gene ID
23580
Swiss Prot
Q9H3Q1
Accession Number
NP_036253
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDC42EP4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDC42EP4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-936
Calculated Molecular Weight
38 kDa
Applications Notes
CDC42EP4 antibody can be used for detection of CDC42EP4 by ELISA at 1:62500. CDC42EP4 antibody can be used for detection of CDC42EP4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CDC42EP4
NCBI Official Name
CDC42 effector protein (Rho GTPase binding) 4
NCBI Organism
Homo sapiens
Background Reference 01
Olsen, J.V., (2006) Cell 127 (3), 635-648.
Other Product Names
CDC42EP4, BORG4, CEP4, KAIA1777, MGC17125, MGC3740
Tested Applications
ELISA, WB
Protein ID
13786127
Physical Properties
Liquid
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