SFN Antibody
Product Specifications
Background
SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
NCBI Gene ID
2810
Swiss Prot
P31947
Accession Number
NP_006133
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SFN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SFN antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-930
Calculated Molecular Weight
28 kDa
Applications Notes
SFN antibody can be used for detection of SFN by ELISA at 1:1562500. SFN antibody can be used for detection of SFN by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SFN
NCBI Official Name
Stratifin
NCBI Organism
Homo sapiens
Background Reference 01
Yang, W., (2008) Cell Cycle 7 (5), 670-682.
Other Product Names
SFN, YWHAS
Tested Applications
ELISA, WB
Protein ID
5454052
Physical Properties
Liquid
Curated Selection
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