ICA1 Antibody

ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ICA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

ICA1 antibody can be used for detection of ICA1 by ELISA at 1:312500. ICA1 antibody can be used for detection of ICA1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.