GBP2 Antibody

Product Specifications

Background

GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) . GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs) . GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) . The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.

NCBI Gene ID

2634

Swiss Prot

P32456

Accession Number

NP_004111

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GBP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Immunology

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GBP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

67 kDa

Applications Notes

GBP2 antibody can be used for detection of GBP2 by ELISA at 1:312500. GBP2 antibody can be used for detection of GBP2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.