KPNA1 Antibody

Recombination activating proteins RAG1 and RAG2 regulate and mediate V (D) J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNA1 interacts with RAG1 and may play a role in V (D) J recombination.Recombination activating proteins RAG1 and RAG2 regulate and mediate V (D) J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V (D) J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KPNA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

KPNA1 antibody can be used for detection of KPNA1 by ELISA at 1:62500. KPNA1 antibody can be used for detection of KPNA1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.