IMPDH1 Antibody
Product Specifications
Background
IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP) . This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10) .
NCBI Gene ID
3614
Swiss Prot
P20839
Accession Number
NP_899066
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IMPDH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IMPDH1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-855
Calculated Molecular Weight
62 kDa
Applications Notes
IMPDH1 antibody can be used for detection of IMPDH1 by ELISA at 1:312500. IMPDH1 antibody can be used for detection of IMPDH1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IMPDH1
NCBI Official Name
IMP (inosine 5'-monophosphate) dehydrogenase 1
NCBI Organism
Homo sapiens
Background Reference 01
Wang, J., (2008) Clin. Pharmacol. Ther. 83 (5), 711-717.
Other Product Names
IMPDH1, DKFZp781N0678, IMPD, IMPD1, LCA11, RP10, sWSS2608
Tested Applications
ELISA, WB
Protein ID
34328928
Physical Properties
Liquid
Curated Selection
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