LIG1 Antibody
Product Specifications
Background
LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
3978
Swiss Prot
P18858
Accession Number
NP_000225
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LIG1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LIG1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
102 kDa
Applications Notes
LIG1 antibody can be used for detection of LIG1 by ELISA at 1:62500. LIG1 antibody can be used for detection of LIG1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
LIG1
NCBI Official Name
Ligase I, DNA, ATP-dependent
NCBI Organism
Homo sapiens
Background Reference 01
Liang, L., (2008) Nucleic Acids Res. 36 (10), 3297-3310.
Other Product Names
LIG1, MGC117397, MGC130025
Tested Applications
ELISA, WB
Protein ID
4557719
Physical Properties
Liquid
Curated Selection
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