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DNALI1 Antibody

Product Specifications

Background

DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS) . Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS) . Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.

NCBI Gene ID

7802

Swiss Prot

O14645

Accession Number

NP_003453

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DNALI1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DNALI1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

31 kDa

Applications Notes

DNALI1 antibody can be used for detection of DNALI1 by ELISA at 1:62500. DNALI1 antibody can be used for detection of DNALI1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

DNALI1

NCBI Official Name

Dynein, axonemal, light intermediate chain 1

NCBI Organism

Homo sapiens

Background Reference 01

Combs, J., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (40), 14883-14888.

Other Product Names

DNALI1, P28, dJ423B22.5, hp28

Tested Applications

ELISA, WB

Protein ID

37595560

Physical Properties

Liquid

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