ENPP6 Antibody
Product Specifications
Background
ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
NCBI Gene ID
133121
Swiss Prot
Q6UWR7
Accession Number
NP_699174
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ENPP6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ENPP6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-754
Calculated Molecular Weight
50 kDa
Applications Notes
ENPP6 antibody can be used for detection of ENPP6 by ELISA at 1:1562500. ENPP6 antibody can be used for detection of ENPP6 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ENPP6
NCBI Official Name
Ectonucleotide pyrophosphatase/phosphodiesterase 6
NCBI Organism
Homo sapiens
Background Reference 01
Sakagami, H., (2005) J. Biol. Chem. 280 (24), 23084-23093.
Other Product Names
ENPP6, MGC33971, NPP6
Tested Applications
ELISA, WB
Protein ID
23503267
Physical Properties
Liquid
Curated Selection
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