EME1 Antibody
Product Specifications
Background
EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]) .
NCBI Gene ID
146956
Swiss Prot
Q96AY2
Accession Number
NP_689676
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EME1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store EME1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
63 kDa
Applications Notes
EME1 antibody can be used for detection of EME1 by ELISA at 1:312500. EME1 antibody can be used for detection of EME1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
EME1
NCBI Official Name
Essential meiotic structure-specific endonuclease 1
NCBI Organism
Homo sapiens
Background Reference 01
Taylor, E.R. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (10), 3757-3762.
Other Product Names
EME1, FLJ31364, MMS4L, SLX2A
Tested Applications
ELISA, WB
Protein ID
260764007
Physical Properties
Liquid
Curated Selection
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