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EME1 Antibody

Product Specifications

Background

EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]) .

NCBI Gene ID

146956

Swiss Prot

Q96AY2

Accession Number

NP_689676

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EME1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store EME1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

63 kDa

Applications Notes

EME1 antibody can be used for detection of EME1 by ELISA at 1:312500. EME1 antibody can be used for detection of EME1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

EME1

NCBI Official Name

Essential meiotic structure-specific endonuclease 1

NCBI Organism

Homo sapiens

Background Reference 01

Taylor, E.R. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (10), 3757-3762.

Other Product Names

EME1, FLJ31364, MMS4L, SLX2A

Tested Applications

ELISA, WB

Protein ID

260764007

Physical Properties

Liquid

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