RDH12 Antibody
Product Specifications
Background
RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3) .The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3) .
NCBI Gene ID
145226
Swiss Prot
Q96NR8
Accession Number
NP_689656
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RDH12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RDH12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-725
Calculated Molecular Weight
35 kDa
Applications Notes
RDH12 antibody can be used for detection of RDH12 by ELISA at 1:312500. RDH12 antibody can be used for detection of RDH12 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RDH12
NCBI Official Name
Retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
NCBI Organism
Homo sapiens
Background Reference 01
Sun, W., (2007) Vision Res. 47 (15), 2055-2066.
Other Product Names
RDH12, FLJ30273, LCA3, RP53, LCA13, SDR7C2
Tested Applications
ELISA, WB
Protein ID
186928839
Physical Properties
Liquid
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