GRPEL2 Antibody
Product Specifications
Background
GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
NCBI Gene ID
134266
Swiss Prot
Q8TAA5
Accession Number
NP_689620
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRPEL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GRPEL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-723
Calculated Molecular Weight
25 kDa
Applications Notes
GRPEL2 antibody can be used for detection of GRPEL2 by ELISA at 1:312500. GRPEL2 antibody can be used for detection of GRPEL2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GRPEL2
NCBI Official Name
GrpE-like 2, mitochondrial (E. coli)
NCBI Organism
Homo sapiens
Background Reference 01
Naylor, D.J., (1998) J. Biol. Chem. 273 (33), 21169-21177.
Other Product Names
GRPEL2, DKFZp451C205, FLJ23713, FLJ33918, Mt-GrpE#2
Tested Applications
ELISA, WB
Protein ID
40255109
Physical Properties
Liquid
Curated Selection
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