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CSNK2A1 Antibody

Product Specifications

Background

Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. CSNK2A1 represents the alpha subunit.Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.

NCBI Gene ID

1457

Swiss Prot

P68400

Accession Number

NP_001886

Host

Rabbit

Reactivity

Human, Mouse, Rat, C. elegans, Drosophila

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSNK2A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CSNK2A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Applications Notes

CSNK2A1 antibody can be used for detection of CSNK2A1 by ELISA at 1:62500. CSNK2A1 antibody can be used for detection of CSNK2A1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CSNK2A1

NCBI Official Name

Casein kinase 2, alpha 1 polypeptide

NCBI Organism

Homo sapiens

Background Reference 01

Lehnert, S., (2008) Oncogene 27 (17), 2390-2400.

Other Product Names

CSNK2A1, CK2A1, CKII, CKII alpha, CSNK2A3

Tested Applications

ELISA, WB

Protein ID

4503095

Physical Properties

Liquid

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