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P2RY12 Antibody

Product Specifications

Background

P2RY12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders.The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.

NCBI Gene ID

5028

Swiss Prot

P47900

Accession Number

NP_795345

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RY12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store P2RY12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

39 kDa

Applications Notes

P2RY12 antibody can be used for detection of P2RY12 by ELISA at 1:312500. P2RY12 antibody can be used for detection of P2RY12 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

P2RY1

NCBI Official Name

Purinergic receptor P2Y, G-protein coupled, 1

NCBI Organism

Homo sapiens

Background Reference 01

Staritz, P., (er) Int. J. Cardiol. (2008) In press.

Other Product Names

P2RY12, ADPG-R, HORK3, P2T (AC), P2Y (AC), P2Y (ADP), P2Y (cyc), P2Y12, SP1999, P2Y1

Tested Applications

ELISA, WB

Protein ID

29029605

Physical Properties

Liquid

Curated Selection

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