SIN3B Antibody
Product Specifications
Background
SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription
NCBI Gene ID
23309
Swiss Prot
O75182
Accession Number
NP_056075
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIN3B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
HCT15 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SIN3B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
133 kDa
Applications Notes
SIN3B antibody can be used for detection of SIN3B by ELISA at 1:62500. SIN3B antibody can be used for detection of SIN3B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SIN3B
NCBI Official Name
SIN3 transcription regulator family member B
NCBI Organism
Homo sapiens
Background Reference 01
Dhanda, R.S., (er) BMC Mol. Biol. 9, 8 (2008) .
Other Product Names
SIN3B, KIAA0700
Tested Applications
ELISA, WB
Protein ID
52138513
Physical Properties
Liquid
Frequently Asked Questions
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