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SPINT2 Antibody

Product Specifications

Background

HAI-2 (SPINT2) is a candidate tumour suppressor gene that is frequently hypermethylated and underexpressed in human HCCs, and the KD-1 domain of HAI-2 is the key region responsible for its anti-invasive function. It is also implicated in human cervical cancer.

NCBI Gene ID

10653

Swiss Prot

O43291

Accession Number

NP_066925

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPINT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10407 - Fetal Heart Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SPINT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

28 kDa

Applications Notes

SPINT2 antibody can be used for detection of SPINT2 by ELISA at 1:62500. SPINT2 antibody can be used for detection of SPINT2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SPINT2

NCBI Official Name

Serine peptidase inhibitor, Kunitz type, 2

NCBI Organism

Homo sapiens

Background Reference 01

Generali, D., Clin. Cancer Res. 13 (2 PT 1), 550-558 (2007) .

Other Product Names

SPINT2, HAI-2, HAI2, Kop, PB, DIAR3

Tested Applications

ELISA, WB

Protein ID

10863909

Physical Properties

Liquid

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