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TGM5 Antibody

Product Specifications

Background

TGM5 belongs to the transglutaminase superfamily, transglutaminase family. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It contributes to the formation of the cornified cell envelope of keratinocytes. Defects in TGM5 are a cause of peeling skin syndrome acral type (APSS) .

NCBI Gene ID

9333

Swiss Prot

O43548

Accession Number

NP_963925

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TGM5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1201 - HeLa Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TGM5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

81 kDa

Applications Notes

TGM5 antibody can be used for detection of TGM5 by ELISA at 1:12500. TGM5 antibody can be used for detection of TGM5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TGM5

NCBI Official Name

Transglutaminase 5

NCBI Organism

Homo sapiens

Background Reference 01

Cassidy, A.J., (2005) Am. J. Hum. Genet. 77 (6), 909-917.

Other Product Names

TGM5, MGC141907, TGM6, TGMX, TGX, TGASE5, TGASEX

Tested Applications

ELISA, WB

Protein ID

94981556

Physical Properties

Liquid

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