TGM5 Antibody
Product Specifications
Background
TGM5 belongs to the transglutaminase superfamily, transglutaminase family. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It contributes to the formation of the cornified cell envelope of keratinocytes. Defects in TGM5 are a cause of peeling skin syndrome acral type (APSS) .
NCBI Gene ID
9333
Swiss Prot
O43548
Accession Number
NP_963925
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TGM5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TGM5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
81 kDa
Applications Notes
TGM5 antibody can be used for detection of TGM5 by ELISA at 1:12500. TGM5 antibody can be used for detection of TGM5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TGM5
NCBI Official Name
Transglutaminase 5
NCBI Organism
Homo sapiens
Background Reference 01
Cassidy, A.J., (2005) Am. J. Hum. Genet. 77 (6), 909-917.
Other Product Names
TGM5, MGC141907, TGM6, TGMX, TGX, TGASE5, TGASEX
Tested Applications
ELISA, WB
Protein ID
94981556
Physical Properties
Liquid
Curated Selection
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