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ST8SIA4 Antibody

Product Specifications

Background

ST8SIA4 catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1) . ST8SIA4, a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus.The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1) . The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

7903

Swiss Prot

Q92187

Accession Number

NP_005659

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ST8SIA4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ST8SIA4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

41 kDa

Applications Notes

ST8SIA4 antibody can be used for detection of ST8SIA4 by ELISA at 1:312500. ST8SIA4 antibody can be used for detection of ST8SIA4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ST8SIA4

NCBI Official Name

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

NCBI Organism

Homo sapiens

Background Reference 01

Schreiber, S.C., (2008) Gastroenterology 134 (5), 1555-1566.

Other Product Names

ST8SIA4, MGC34450, MGC61459, PST, PST1, SIAT8D, ST8SIA-IV

Tested Applications

ELISA, WB

Protein ID

5031999

Physical Properties

Liquid

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