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CLN6 Antibody

Product Specifications

Background

CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

NCBI Gene ID

54982

Swiss Prot

Q9NWW5

Accession Number

NP_060352

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLN6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLN6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

36 kDa

Applications Notes

CLN6 antibody can be used for detection of CLN6 by ELISA at 1:1562500. CLN6 antibody can be used for detection of CLN6 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CLN6

NCBI Official Name

Ceroid-lipofuscinosis, neuronal 6, late infantile, variant

NCBI Organism

Homo sapiens

Background Reference 01

Heine, C., (2007) Mol. Membr. Biol. 24 (1), 74-87.

Other Product Names

CLN6, FLJ20561, HsT18960, nclf, CLN4A

Tested Applications

ELISA, WB

Protein ID

8923532

Physical Properties

Liquid

Frequently Asked Questions

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