CLN6 Antibody
Product Specifications
Background
CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
NCBI Gene ID
54982
Swiss Prot
Q9NWW5
Accession Number
NP_060352
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLN6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLN6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-214
Calculated Molecular Weight
36 kDa
Applications Notes
CLN6 antibody can be used for detection of CLN6 by ELISA at 1:1562500. CLN6 antibody can be used for detection of CLN6 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CLN6
NCBI Official Name
Ceroid-lipofuscinosis, neuronal 6, late infantile, variant
NCBI Organism
Homo sapiens
Background Reference 01
Heine, C., (2007) Mol. Membr. Biol. 24 (1), 74-87.
Other Product Names
CLN6, FLJ20561, HsT18960, nclf, CLN4A
Tested Applications
ELISA, WB
Protein ID
8923532
Physical Properties
Liquid
Curated Selection
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