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GCS1 Antibody

Product Specifications

Background

GCS1 is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.

NCBI Gene ID

7841

Swiss Prot

Q13724

Accession Number

NP_006293

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GCS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1201 - HeLa Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GCS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

92 kDa

Applications Notes

GCS1 antibody can be used for detection of GCS1 by ELISA at 1:312500. GCS1 antibody can be used for detection of GCS1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

MOGS

NCBI Official Name

Mannosyl-oligosaccharide glucosidase

NCBI Organism

Homo sapiens

Background Reference 01

Hardt, B., (2003) Glycobiology 13 (3), 159-168.

Other Product Names

GCS1, DER7, GCS1, CDG2B, CWH41

Tested Applications

ELISA, WB

Protein ID

149999606

Physical Properties

Liquid

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