4'-Nitroacetophenone

4'-Nitroacetophenone is a nitroaromatic compound. 4'-Nitroacetophenone is an important organic synthetic intermediate, which can be used for the synthesis of other active compounds such as Chloramphenicol (HY-B0239) [1][2][3].

Product Specifications

CAS Number

[100-19-6]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Drug Intermediate

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-nitroacetophenone.html

Purity

99.93

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CC(C1=CC=C([N+]([O-])=O)C=C1)=O

Molecular Formula

C8H7NO3

Molecular Weight

165.15

Precautions

H302, H315, H319, H335

References & Citations

[1]KLOSA J. et al [Studies on the exchange of diazonium group with nitro group for the preparation of p-nitroacetophenone. III. Synthesis of chloramphenicol]. Arch Pharm Ber Dtsch Pharm Ges. 1953;286 (8) :416-8. Undetermined Language.|[2]Pérez-Rebolledo A, et al. 4-nitroacetophenone-derived thiosemicarbazones and their copper (II) complexes with significant in vitro anti-trypanosomal activity. Eur J Med Chem. 2008 May;43 (5) :939-48.|[3]Alam A, et al. Novel Bis-Schiff's base derivatives of 4-nitroacetophenone as potent α-glucosidase agents: Design, synthesis and in silico approach. Bioorg Chem. 2022 Nov;128:106058.