ATP2A3 Antibody
Product Specifications
Background
ATP2A3 is one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
489
Swiss Prot
Q93084
Accession Number
NP_005164
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP2A3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ATP2A3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-148
Calculated Molecular Weight
109 kDa
Applications Notes
ATP2A3 antibody can be used for detection of ATP2A3 by ELISA at 1:312500. ATP2A3 antibody can be used for detection of ATP2A3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ATP2A3
NCBI Official Name
ATPase, Ca++ transporting, ubiquitous
NCBI Organism
Homo sapiens
Background Reference 01
Korosec, B., (2008) Cancer Genet. Cytogenet. 181 (2), 112-118.
Other Product Names
ATP2A3, SERCA3
Tested Applications
ELISA, WB
Protein ID
28373103
Physical Properties
Liquid
Curated Selection
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