TMEM48 Antibody
Product Specifications
Background
TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
NCBI Gene ID
55706
Swiss Prot
Q9BTX1
Accession Number
NP_060557
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMEM48.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TMEM48 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
76 kDa
Applications Notes
TMEM48 antibody can be used for detection of TMEM48 by ELISA at 1:62500. TMEM48 antibody can be used for detection of TMEM48 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NDC1
NCBI Official Name
NDC1 transmembrane nucleoporin
NCBI Organism
Homo sapiens
Background Reference 01
Olsen, J.V., (2006) Cell 127 (3), 635-648.
Other Product Names
TMEM48, FLJ10407, FLJ12556, FLJ34120, NDC1, RP4-654H19.1, NET3, TMEM48
Tested Applications
ELISA, WB
Protein ID
271398350
Physical Properties
Liquid
Curated Selection
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