ROBO2 Antibody
Product Specifications
Background
ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. ROBO2 is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for ROBO2.This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
NCBI Gene ID
6092
Swiss Prot
Q9HCK4
Accession Number
NP_002933
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ROBO2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ROBO2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
151 kDa
Applications Notes
ROBO2 antibody can be used for detection of ROBO2 by ELISA at 1:1562500. ROBO2 antibody can be used for detection of ROBO2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ROBO2
NCBI Official Name
Roundabout, axon guidance receptor, homolog 2 (Drosophila)
NCBI Organism
Homo sapiens
Background Reference 01
Bausserman, L.L., (2008) J. Am. Soc. Nephrol. 19 (4), 825-831.
Other Product Names
ROBO2, KIAA1568, SAX3
Tested Applications
ELISA, WB
Protein ID
61888896
Physical Properties
Liquid
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