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ROBO2 Antibody

Product Specifications

Background

ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. ROBO2 is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for ROBO2.This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

NCBI Gene ID

6092

Swiss Prot

Q9HCK4

Accession Number

NP_002933

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ROBO2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ROBO2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

151 kDa

Applications Notes

ROBO2 antibody can be used for detection of ROBO2 by ELISA at 1:1562500. ROBO2 antibody can be used for detection of ROBO2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ROBO2

NCBI Official Name

Roundabout, axon guidance receptor, homolog 2 (Drosophila)

NCBI Organism

Homo sapiens

Background Reference 01

Bausserman, L.L., (2008) J. Am. Soc. Nephrol. 19 (4), 825-831.

Other Product Names

ROBO2, KIAA1568, SAX3

Tested Applications

ELISA, WB

Protein ID

61888896

Physical Properties

Liquid

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