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LRP8 Antibody

Product Specifications

Background

LRP8 is an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL) . The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins.This gene encodes an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL) . The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.

NCBI Gene ID

7804

Swiss Prot

B1AMT8

Accession Number

NP_059992

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LRP8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LRP8 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

74 kDa

Applications Notes

LRP8 antibody can be used for detection of LRP8 by ELISA at 1:1562500. LRP8 antibody can be used for detection of LRP8 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

LRP8

NCBI Official Name

Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

NCBI Organism

Homo sapiens

Background Reference 01

Hoe, H.S., (2008) J. Biol. Chem. 283 (10), 6288-6299.

Other Product Names

LRP8, APOER2, HSZ75190, MCI1, LRP-8, RP5-1024G6.8

Tested Applications

ELISA, WB

Protein ID

61744467

Physical Properties

Liquid

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