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TRPM2 Antibody

Product Specifications

Background

TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NCBI Gene ID

7226

Swiss Prot

O94759

Accession Number

NP_003298

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRPM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRPM2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=25-953

Calculated Molecular Weight

171 kDa

Applications Notes

TRPM2 antibody can be used for detection of TRPM2 by ELISA at 1:62500. TRPM2 antibody can be used for detection of TRPM2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TRPM2

NCBI Official Name

Transient receptor potential cation channel, subfamily M, member 2

NCBI Organism

Homo sapiens

Background Reference 01

Hecquet, C.M., (2008) Circ. Res. 102 (3), 347-355.

Other Product Names

TRPM2, EREG1, KNP3, LTRPC2, MGC133383, NUDT9H, NUDT9L1, TRPC7

Tested Applications

ELISA, WB

Protein ID

4507689

Physical Properties

Liquid

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