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MARCH7 Antibody

Product Specifications

Background

MARCH7 is an E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

NCBI Gene ID

64844

Swiss Prot

Q9H992

Accession Number

NP_073737

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Homeostasis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1309 - Human Placenta Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MARCH7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

78 kDa

Applications Notes

MARCH7 antibody can be used for detection of 40244 by ELISA at 1:62500. MARCH7 antibody can be used for detection of 40244 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

MARCH7

NCBI Official Name

Membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase

NCBI Organism

Homo sapiens

Background Reference 01

Muthukumarana, P.A., Int. Immunopharmacol. 6 (13-14), 1993-2001 (2006) .

Other Product Names

MARCH7, AXO, AXOT, DKFZP586F1122, MARCH-VII, RNF177

Tested Applications

ELISA, WB

Protein ID

12383066

Physical Properties

Liquid

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