MARCH5 Antibody
Product Specifications
Background
MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L) .MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]) .
NCBI Gene ID
54708
Swiss Prot
Q9NX47
Accession Number
NP_060294
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MARCH5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
31 kDa
Applications Notes
MARCH5 antibody can be used for detection of MARCH5 by ELISA at 1:1562500. MARCH5 antibody can be used for detection of MARCH5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MARCH5
NCBI Official Name
Membrane-associated ring finger (C3HC4) 5
NCBI Organism
Homo sapiens
Background Reference 01
Karbowski, M., (2007) J. Cell Biol. 178 (1), 71-84.
Other Product Names
MARCH5, FLJ20445, MARCH-V, MITOL, RNF153
Tested Applications
ELISA, WB
Protein ID
8923415
Physical Properties
Liquid
Curated Selection
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