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TJP2 Antibody

Product Specifications

Background

Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.

NCBI Gene ID

9414

Swiss Prot

A2A3H9

Accession Number

NP_963923

Host

Rabbit

Reactivity

Human, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TJP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TJP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

118 kDa

Applications Notes

TJP2 antibody can be used for detection of TJP2 by ELISA at 1:62500. TJP2 antibody can be used for detection of TJP2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TJP2

NCBI Official Name

Tight junction protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Bel (2008) Hum. Genet. 123 (3), 267-272.

Other Product Names

TJP2, MGC26306, X104, ZO-2, ZO2, DFNA51, DUP9q21.11, C9DUPq21.11

Tested Applications

ELISA, WB

Protein ID

42518065

Physical Properties

Liquid

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