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ELMO3 Antibody

Product Specifications

Background

ELMO3 is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.

NCBI Gene ID

79767

Swiss Prot

Q96BJ8

Accession Number

NP_078988

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ELMO3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ELMO3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

87 kDa

Applications Notes

ELMO3 antibody can be used for detection of ELMO3 by ELISA at 1:312500. ELMO3 antibody can be used for detection of ELMO3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ELMO3

NCBI Official Name

Engulfment and cell motility 3

NCBI Organism

Homo sapiens

Background Reference 01

Gumienny, T.L., (2001) Cell 107 (1), 27-41.

Other Product Names

ELMO3, CED-12, CED12, ELMO-3, FLJ13824

Tested Applications

ELISA, WB

Protein ID

87298935

Physical Properties

Liquid

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