CALCRL Antibody
Product Specifications
Background
CALCRL is the receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
NCBI Gene ID
10203
Swiss Prot
Q16602
Accession Number
NP_005786
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CALCRL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CALCRL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
53 kDa
Applications Notes
CALCRL antibody can be used for detection of CALCRL by ELISA at 1:12500. CALCRL antibody can be used for detection of CALCRL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CALCRL
NCBI Official Name
Calcitonin receptor-like
NCBI Organism
Homo sapiens
Background Reference 01
Eskesen, K., Ideggyogy Sz 60 (11-12), 459-466 (2007) .
Other Product Names
CALCRL, CGRPR, CRLR
Tested Applications
ELISA, WB
Protein ID
5031621
Physical Properties
Liquid
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