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CALCRL Antibody

Product Specifications

Background

CALCRL is the receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

NCBI Gene ID

10203

Swiss Prot

Q16602

Accession Number

NP_005786

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CALCRL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction, Immunology

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CALCRL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

53 kDa

Applications Notes

CALCRL antibody can be used for detection of CALCRL by ELISA at 1:12500. CALCRL antibody can be used for detection of CALCRL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CALCRL

NCBI Official Name

Calcitonin receptor-like

NCBI Organism

Homo sapiens

Background Reference 01

Eskesen, K., Ideggyogy Sz 60 (11-12), 459-466 (2007) .

Other Product Names

CALCRL, CGRPR, CRLR

Tested Applications

ELISA, WB

Protein ID

5031621

Physical Properties

Liquid

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