LSS Antibody
Product Specifications
Background
LSS catalyzes the conversion of (S) -2,3 oxidosqualene to lanosterol. It is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene catalyzes the conversion of (S) -2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
4047
Swiss Prot
P48449
Accession Number
NP_002331
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LSS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LSS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
83 kDa
Applications Notes
LSS antibody can be used for detection of LSS by ELISA at 1:312500. LSS antibody can be used for detection of LSS by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
LSS
NCBI Official Name
Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
NCBI Organism
Homo sapiens
Background Reference 01
Ma, J., (2007) Atherosclerosis 191 (1), 63-72.
Other Product Names
LSS, OSC
Tested Applications
ELISA, WB
Protein ID
47933395
Physical Properties
Liquid
Curated Selection
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