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LSS Antibody

Product Specifications

Background

LSS catalyzes the conversion of (S) -2,3 oxidosqualene to lanosterol. It is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene catalyzes the conversion of (S) -2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

4047

Swiss Prot

P48449

Accession Number

NP_002331

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LSS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LSS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

83 kDa

Applications Notes

LSS antibody can be used for detection of LSS by ELISA at 1:312500. LSS antibody can be used for detection of LSS by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

LSS

NCBI Official Name

Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)

NCBI Organism

Homo sapiens

Background Reference 01

Ma, J., (2007) Atherosclerosis 191 (1), 63-72.

Other Product Names

LSS, OSC

Tested Applications

ELISA, WB

Protein ID

47933395

Physical Properties

Liquid

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