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CYP4B1 Antibody

Product Specifications

Background

CYP4B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.

NCBI Gene ID

1580

Swiss Prot

P13584

Accession Number

NP_000770

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP4B1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CYP4B1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

59 kDa

Applications Notes

CYP4B1 antibody can be used for detection of CYP4B1 by ELISA at 1:312500. CYP4B1 antibody can be used for detection of CYP4B1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CYP4B1

NCBI Official Name

Cytochrome P450, family 4, subfamily B, polypeptide 1

NCBI Organism

Homo sapiens

Background Reference 01

Hiratsuka, M., (2004) Drug Metab. Pharmacokinet. 19 (2), 114-119.

Other Product Names

CYP4B1, CYPIVB1, P-450HP

Tested Applications

ELISA, WB

Protein ID

153218660

Physical Properties

Liquid

Frequently Asked Questions

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