SMNDC1 Antibody
Product Specifications
Background
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
NCBI Gene ID
10285
Swiss Prot
O75940
Accession Number
NP_005862
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMNDC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Apoptosis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMNDC1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-633
Calculated Molecular Weight
27 kDa
Applications Notes
SMNDC1 antibody can be used for detection of SMNDC1 by ELISA at 1:1562500. SMNDC1 antibody can be used for detection of SMNDC1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SMNDC1
NCBI Official Name
Survival motor neuron domain containing 1
NCBI Organism
Homo sapiens
Background Reference 01
Little, J.T. (2008) J. Biol. Chem. 283 (13), 8145-8152.
Other Product Names
SMNDC1, SMNR, SPF30, TDRD16C
Tested Applications
ELISA, WB
Protein ID
5032113
Physical Properties
Liquid
Curated Selection
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